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Welcome
Message from the Executive Director:
Incredible discoveries continue to come from the Evelyn F. and William L. McKnight Brain Institute (MBI). Given our original goal of focusing the MBI’s endeavors on neural diagnostics and neural therapeutics, we are definitely making progress toward translating basic and clinical science to new therapeutic protocols for a variety of neurological disorders that affect the central nervous system (CNS). With countless announcements of breakthroughs from our gifted basic science and clinical investigators in everything from regenerative medicine, to the basis of normal and abnormal memory function, to new cell, molecular and surgical therapies for Parkinson’s disease, dystonia, brain cancer, and addiction, all of us in the MBI are incredibly optimistic that the future definitely looks promising for treating and hopefully curing all neurological diseases.
Cores to translate into therapies:
We have six major cores or platforms for research and discovery in the MBI.
- 1. Age-Related Memory Loss and Cognition
- 2. Brain Cancer
- 3. CNS Injury (including traumatic brain injury and stroke)
- 4. Chronic Neurological Diseases (including Parkinson’s disease, ALS and Huntington’s disease, Multiple sclerosis, Alzheimer’s disease, epilepsy, and other neuromuscular disorders)
- 5. Development, Regeneration, and Rehabilitation
- 6. Mental Health, Neurobehavioral Sciences, Psychiatry (including schizophrenia, depression, obsessive compulsive disorder, and addiction)
In addition to incorporating the work of many colleges (e.g. Medicine, Allied Health, Liberal Arts and Sciences, Engineering, Veterinary Medicine, Dentistry, and Engineering), and collaborating with all of the distinguished centers and programs on campus, we will continue to focus our in-house and cross-campus departments (over 50 of them) and investigators (over 300 of them) on developing powerful clinical trials to treat a variety of CNS disorders.
We have recruited additional new faculty members in the areas of aging brain plasticity, stroke, Alzheimer’s disease, glioma in the evolving field of regenerative biology and medicine who are working toward the creation of new programmatic laboratories and clinical trial centers that are dedicated to translating the discoveries from the six cores into powerful new therapies and cures. The MBI has also launched several new “working group think tanks” in the areas of dystonia research, regeneration biology, and neurodegenerative diseases and stroke, making all of us continue to dedicate our work to the mission of the Evelyn F. and William L. McKnight Brain Institute to be not only the best in the world, but also to rapidly apply our growing knowledge of the nervous system toward curing all debilitating neurological diseases. I look forward to continuing to announce our many exciting breakthroughs in the world of restorative neuroscience. Since we now have many of the tools, investigators and working groups in place, and the fields of neuro-imaging, models of neurological disease, and regenerative medicine are continuing to move rapidly ahead, I am hopeful that you will continue seeing these announcements coming at a swift and steady pace.
Dennis A. Steindler, Ph.D.
Executive Director
The Evelyn F. and William L. McKnight Brain Institute
Joseph J. Bagnor/Shands Professor of Medical Research
The University of Florida

