BCH 6744 Lecture Notes

Syllabus

Lecture 1: General Overview

Lecture 2: Sample Preparation

Lecture 3: Crystallization

Lecture 4: Crystal Preparation

Lecture 5: Diffraction Theory: Braggs Law

Lecture 6: Data Collection / Instrumentation

Lecture 7: Data Collection Procedure

Lecture 8: Space Group Determination: Crystal Symmetry

Lecture 9: Data Processing and Reduction

Lecture 10: Fourier Transforms

Lecture 11: Phase Determination: Heavy atom and MAD

Lecture 12: Phase Determination: Molecular Replacement

Lecture 13: Model Building: Map Interpretation

Practical 1: Crystallization of Lysozyme

Practical 2: Diffraction Data Collection

Practical 3: Data Processing and Reduction

Practical 4: Phasing and Model Building

Practical 5: Refinement and Structure Function Analysis